Cause
The etiology and pathogenesis of depression involve biochemistry, neuroendocrine, neuroimmunology, abnormal sleep and EEG, brain imaging, genetics, psychosocial factors, etc.
Basic cause
The etiology and pathogenesis of this disease are still unclear. A large number of research data suggest that genetic factors, neurobiochemical factors, and psychosocial factors have a significant impact on the occurrence of this disease.
Predisposing factors
There is no clear predisposing factor for this disease, but at present, stressful life events, pessimistic personality traits, history of other mental illnesses, severe chronic diseases, alcoholism, drug abuse, etc. are closely related to the onset of depression .